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Principal Investigators
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Post-Doctoral Fellows
- Ph.D. Candidates
- M.S. Candidates
Associate Members
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Ph.D. Candidates
Jonghoon Lee (Biological Engineering)

Research Interests
I have an interest in the dynamic behavior of biological molecules such as RKIP and its biological consequences in the context of the inter-linked signal transduction pathways. And I am also interested in the systems biology on colorectal cancer using multi-agent based modeling methods.

Keywords : Cancer systems biology, RKIP, signal transduction pathway, multi-agent modeling.

Soo-Jeong Hwang(Medical Science and Engineering/DDS, Preventive dentistry)

Research Interests
I want to construct the prediction model of oromaxillofacial disease using systems biology and develop the preventive programme. I am also interested in toothorganogenesis and osteogenesis.

Keywords : Systems biology, Systems immunology, Stem cell development

Sang-Min Park (Bio and Brain Engineering)

Research Interests
Scientist, philosopher and writer who elucidates the mystery of brain; this is my future self. I have been dreaming of establish the consilience of macroscopic view and microscopic view in neuroscience. Underlying principle suppose to be in the place, where top-down and bottom-up approaches meet. Emergent property & complex network science may penetrate the levels of hierarchy and furnish the multi-scale insights to 'What is Interlligence? How it emerges? and Why?'.

Keywords : Systems brain theory, Neural network dynamics, Emergent property

Jae Il Joo (Biological Science / Computer Science)

Research Interests
All the cells are controlled by biological systems of genes and proteins. Unfortunately, the biological systems are nonlinear systems but the conventional biological methods have limitation to unravel the nonlinear systems. Systems biology can overcome the limitation of the conventional biology to analyze the nonlinear systems. So I want to study cancer biology and developmental biology, which are the most complex problems in biology, through systems biology.

Keywords : cancer biology, developmental biology, stem cell

So Yeong Jang (Electronic Engineering)

Research Interests
There are a lot of unsolved problems of brain with emergent properties. I think that there is a set of simple regulations in brain network for complex output that we cannot understand intuitively. I want to analyze the mechanism and reasoning of brain network dynamics through the network control theory.

Keywords : systems biology, network dynamics, network biology

Sea Choi (Cell Biology)

Research Interests
Cancer research encompasses studies on cell cycle regulation, apoptosis, and tumor initiation, progression as well as metastasis that are involved in different singling pathways, underpinning the efforts to evaluate new therapies and tools to treat patients with cancer. Tumorigenic and stem cells conceptually share a similarity that they are capable of proliferating extensively. I am particularly interested in elucidating the dialogue between the tumor cells and molecular basis of stem cell self-renewal which can contribute to cancer progression and possibly reversion. I also want to apply systems biology to unravel this complicated molecular interactions.

Keywords : cancer biology, stem cell biology and regenerative medicine, signaling pathways

Jeong-Ryeol Gong (Biomedical Science)

Research Interests
Cancer is basically a disease of uncontrolled cell division beyond the surveillance of immune cells. Thus, Immunological cancer reversion is the best anti-cancer therapeutic strategy. For this purpose, a network-based treatment strategy is established using high-throughput data including single-cell RNA seq data. If cancer cells can be returned to an immunologically vulnerable state, the cancer is expected to be removed by immune cells and cured naturally.

Keywords : Cancer systems biology, Immunology, Bioinformatics

Yunseong Kim (Bio and Brain Engineering)

Research Interests
The first goal of my research is to mapping or visualizing the cell states of cancer. Based on these maps, I want to control the cancer cell and lead them into apoptosis with targeted anti-cancer drugs. Furthermore, I hope to rewind the cancer cells into normal cells by modulating the signal transduction pathway.

Keywords : cancer systems biology, apoptosis, rewinding cell fate, targeted anti-cancer drugs

Jongwan Kim (Biology and Mathematics)

Research Interests
I'm interested in systems biology. I want to analyze the cell as a gene regulatory network using mathematical modeling method. I assume that life network dynamics is chaotic so there are simple principles which make up a complex life phenomenon. I expect the mathematical models to show the principles of complex life phenomena.

Keywords : systems biology, network control, mathematical modeling

Younghyun Han (Computer science)

Research Interests
To know what is life, we have to see life as a system. So I would like to analyze and understand life system by mathematical modeling and computer simulation. Also, I am interested in building tailored therapy strategy through systems biology.

Keywords : systems biology

Hongjun Chang (Biology)

Research Interests
I'm interested in the computational modeling of biological neural networks to explain experimental results such as neural oscillation, and applying the control theory of networks to biological interaction networks and neural networks.

Keywords : neural network modeling, network theory

Chun-Kyung Lee (Biology)

Research Interests
Reductionism approach is still needed to study cells in depth. But that's insufficient in uncovering the fundamental biological mechanisms. I want to integrate all information obtatined through experimental biological discoveries and reveal the mechanisms in holism. Especially, I am interested in developing therapeutics to block metastatsis that would be fatal for cancer patients.

Keywords : systems biology, cancer biology

Sugyun An (biomedical science / bioengineering)

Research Interests
The data that we now generate overwhelm our abilities of interpretation. My research goal is to appropriately interpret the biological data using system biology and bioinformatics. I am especially interested in health and longevity and I hope that my research contributes to the healthy life of people.

Keywords : systems biology, bioinformatics, longevity

Uiryong Kang (Life Sciences / Electrical Engineering)

Research Interests
Without doubt, brain is one of the most vital organ in maintaining normal body function. Besides, it is probably the most efficient computing machinery mankind has ever found. Because this marvelous organ has hierarchical structures and properties of complex network at all scales, it should be studied by tools of network science in a systematic manner. In this context, I have a great interest in figuring out hidden scientific principles of brain function retained in various brain networks.

Keywords : network neuroscience, comparative connectomics, network control theory

Kim nam hee (Bio and brain Engineering)

Research Interests
I'm interested in cancer metastasis. To understand biology better and to control cells, I want to analyze biological data and gene regulatory network using systems biology.

Keywords : cancer biology, network theory, systems biology

M.S. Candidates
Junsoo Kang (Bio and Brain Engineering / Biological Sciences)

Research Interests
The recent advances in artificial intelligence technology along with the strides in systems biology have brought about new era of bio-data science. I wish to utilize ideas from both deep learning and network control theory to understand biological systems, notably the aging-related pathways and the brain networks, better.

Keywords : systems biology, network control theory, machine learning, deep learning

Ji-Hye Choi (Bio and Brain Engineering)

Research Interests
I am interested in how biology works in terms of network, and what happens to it when its component is malfunctioning due to diseases, especially cancer. Although there has been a lot of attempts to treat cancer, very few of them are successful while most of them fail. I want to study why cancer therapies fail for some patients, how the cancer drug resistance arises and what is the effective way to overcome it in a view of systems biology.

Keywords : systems biology, cancer, drug resistance

Hoon min Kim (Physics / Bio and Brain Engineering)

Research Interests
As biological systems of cells contain numerous components with complex regulating relations and their dynamics unknown, it is difficult to predict biological behaviors of complex diseases for certain conditions. Reconstructing the regulatory network for computational modelling from high-throughput experimental data would provide optimal treatment strategy for complex diseases with network control theory combined. My research interest lies on network model reconstruction strategy and network control theory.

Keywords : systems biology, network inference, control theory

Chang-young Joung (Bio-technology)

Research Interests
The development of high throughput sequencing technology has fundamentally changed the way we approach biological issues. It created a new field called bioinformatics, and at the same time, the importance of systems biology has emerged. Systems biology can create models that reflect the accumulated data from bioinformatics. My research goal is to create a new model that predicts the drug response of cancer using systems biology. I hope my model can be used to find optimal drug combinations.

Keywords : Systems biology, Cancer biology, Bioinformatics