Myoungbo Kang (Biotechnology & Statistic)
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| mbkang@kaist.ac.kr
Research Interests I aim to conduct integrated research, spanning biology to computer modeling and simulations. While traditional cancer treatments mainly involve chemotherapy or surgery, there's a growing expectation that addressing the complexity of gene regulatory networks could lead to a more foundational and reversible approach to cancer treatment. My goal is to extract insights from extensive datasets, understand biological networks, and experimentally validate these findings, contributing to innovative and effective cancer therapeutic strategies.
Keywords Cancer biology, Reverse control, Systems biology
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Yoonsu Na (Biology & Convergence Software)
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| ysna99@kaist.ac.kr
Research Interests As human health and cancer treatment is becoming one of the most important issue among the world, I think Systems Biology is a key breakthrough to deal with these issues. By modeling and analyzing various biological networks, we might be able to find novel target which is engaged in reversion of tumor to normal state. With concepts of Boolean network and control theory, I think it is not impossible to make a therapeutic strategies for unconquered cancer types.
Keywords Network modeling, Network control, Cancer Biology
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Ferio Brahmana (Engineering Physics)
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| feriobrahmana@kaist.ac.kr
Research Interests My research interest lies in comprehending biological systems, particularly human cells, as complex dynamical entities. By conceptualizing these systems as dynamical systems, I aim to establish computable mathematical models that deepen our understanding of the intricate dynamics governing human cells. The overarching goal is to leverage this understanding to exercise control over human cell systems through computer simulation and a systems biology approach. With precise control mechanisms, there is significant potential to navigate the complex interplay of multi-interactions within human cells. I believe this approach holds promise for addressing and combating complex diseases, such as cancer, aging, and immune-related disorders, offering an intriguing perspective like the reverse control theory in the context of fighting diseases like cancer or aging.
Keywords System Biology, Network Control, Reverse Control Theory
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Junseo Seo (Systems Biomedical Science)
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| juneseo99@kaist.ac.kr
Research Interests I focus on the interdisciplinary field of bioinformatics, single-cell genomics, spatial transcriptomics, and systems biology. My research primed on constructing reliable gene regulatory networks and uncovering key factors that regulate these networks, driving changes in biological phenotypes. By analyzing such gene regulatory networks from single-cell or spatial data, my goal is to reveal and control cell fate decisions. I also explore processes such as differential gene expression and cellular trajectory construction to gain deeper insights into cellular behavior. Ultimately, I aim to simulate these complex processes computationally, with the long-term vision of developing strategies to manipulate cell fate, potentially leading to breakthroughs in the treatment and reversion of cancer and other severe diseases.
Keywords Bioinformatics, Single cell genomics, Spatial transcriptomics, Systems biology
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Minkyung Kim (Life Science & Biological Information SW)
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| minkyung32@kaist.ac.kr
Research Interests I want to research to advance healthcare infrastructure and broaden patient treatment options through personalized medicine. Personalized medicine provides treatment strategies based on an individual's genome, but it targets only specific genetic markers. It can overlook the complex interactions among these markers. Therefore, I think it is crucial to understand the intricate interactions within gene regulatory networks using a systems biology approach. Through computer simulations, I aim to discover therapeutic targets that can lead to more effective cancer treatments. This work will contribute to the advancement of precision medicine, ultimately aiming to enhance treatment options for patients.
Keywords Cancer Biology, System biology, Bioinformatics
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